Coxsackie Virus and its Effect on Human Health: A review

Section: Review Articles
Issue
Vol. 34 No. 4 (2025): Volume 34 Issue 4
Published
Oct 1, 2025
Pages
97-104

Abstract

In low- and middle-income countries, coxsackievirus infections constitute a serious public health concern, especially for young children and newborns. Many human ailments, such as hand, foot, and mouth disease, as well as diseases of the heart, lungs, and muscles, are brought on by these infections, which are common around the world. Coxsackie virus infections typically cause mild flu-like symptoms and resolve on their own. However, in certain situations, they might progress to more serious diseases. According to previous studies, around 50% of affected children do not exhibit any symptoms. Others experience a sudden high temperature, muscle aches, and headache; some also experience nausea, stomach pain, or sore throats. Coxsackievirus infections have a brief incubation period, lasting one to five days. A youngster with a Coxsackievirus infection may only feel hot and have no other symptoms. Most children's fevers endure around three days and then disappear.


In this review, we will provide a brief virus from its initial discovery to the laboratory techniques used to diagnose it, in addition to reviewing the epidemiological data,  which offer detailed information on the diversity and distribution of the many Coxsackievirus types. We will also highlight the most important disease it causes, which is hand, foot, and mouth disease.

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Authors

Manar Fawzi Altaie

Department of Biology, College of Science, University of Mosul, Mosul, Iraq

Elaph Madallah Shuwaikh AL-Qaisi

Department of Emergency, Al-Dour Technical Institute, Northern Technical University, Mosul, Iraq

Anmar Ahmed Altaie

Department of Biology, College of Science, University of Mosul, Mosul, Iraq

Identifiers

https://doi.org/10.33899/jes.v34i4.49252
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[1]
M. F. . Altaie, E. M. S. . AL-Qaisi, and A. A. . Altaie, “Coxsackie Virus and its Effect on Human Health: A review”, JES, vol. 34, no. 4, pp. 97–104, Oct. 2025.
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