فصل وتشخيص بعض المركبات الفعالة من بذور نبات الحرنكش العراقي Physalis angulata L. باستخدام تقنيات الكروماتوغرافيا
الصفحات
115-125الكلمات المفتاحية:
الملخص
هدفت هذه الدراسة الى دراسة التركيب الكيميائي النباتي لنوع Physalis angulata L. الذي تم جمعه من ناحية ربيعة غربي مدينة الموصل شمال العراق وتم اختيار البذور لتشخيص ماتحتويه من مركبات فعالة باستخدام تقنيات الكروماتوغرافية من خلال استخلاص المركبات الفعالة باستخدام جهاز Soxhlet، اذ أظهرت النتائج تشخيص ستة مركبات فينولية من المستخلص الكحولي 70% بواسطة HPLC بعد التحلل الحامضي وهي: (Quercetin، Apigenin، Ferulic acid، P-coumaric acid، Gallic acid، وChlorogenic). وسجل اعلى تركيزللمركبChlorogenic في المستخلص بلغ 0.0904mg\ml . و أربعة عشر مركب باستخدام تقنية GC-MS لنفس المستخلص الخام وكان ابرزها (17-Octadecynoic acid و3-Hexanol و 1,2-Benzenedicarboxylic acid و Heptanoic acid, 2-ethylو Lauric acid). كما وشخصت ستة أنواع من الاحماض الدهنية (Oleic، Stearic، Linoleic، Palmatic، Arachidonic، Linolenic) من مستخلص الايثر بترولي المتصوبن بوساطة تقنية GLC، وسجل الحامض الدهني Linoleic في المستخلص النباتي اعلى تركيز بلغ 19.80 %. تشير هذه النتائج احتواء بذور نبات الحرنكش P. angulata L. على مركبات ذات أهمية طبية تفتح المجال الى إمكانية استخدامه في تطبيقات دوائية علاجية مستقبلا.
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